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Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol800575z
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dc.titleSolid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases
dc.contributor.authorYang, P.-Y.
dc.contributor.authorWu, H.
dc.contributor.authorLee, M.Y.
dc.contributor.authorXu, A.
dc.contributor.authorSrinivasan, R.
dc.contributor.authorYao, S.Q.
dc.date.accessioned2014-06-23T05:49:49Z
dc.date.available2014-06-23T05:49:49Z
dc.date.issued2008-05-15
dc.identifier.citationYang, P.-Y., Wu, H., Lee, M.Y., Xu, A., Srinivasan, R., Yao, S.Q. (2008-05-15). Solid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases. Organic Letters 10 (10) : 1881-1884. ScholarBank@NUS Repository. https://doi.org/10.1021/ol800575z
dc.identifier.issn15237060
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/77010
dc.description.abstractAn efficient strategy for the solid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases is described. The method is highlighted by its compatibility with readily available building blocks, as well as its ability to accommodate different functional groups. A 249-member library has thus far been successfully synthesized, characterized, and screened against Caspase-1, -3 and -7. © 2008 American Chemical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/ol800575z
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1021/ol800575z
dc.description.sourcetitleOrganic Letters
dc.description.volume10
dc.description.issue10
dc.description.page1881-1884
dc.identifier.isiut000255694100001
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