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Title: Soft-lithography-mediated submicrometer patterning of self-assembled monolayer of hemoglobin on ITO surfaces
Authors: Fang, A. 
Ng, H.
Su, X.
Li, S.F.Y. 
Issue Date: 13-Jun-2000
Citation: Fang, A., Ng, H., Su, X., Li, S.F.Y. (2000-06-13). Soft-lithography-mediated submicrometer patterning of self-assembled monolayer of hemoglobin on ITO surfaces. Langmuir 16 (12) : 5221-5226. ScholarBank@NUS Repository.
Abstract: The recent direct fabrication of micropatterned arrays of active biomolecules has received overwhelming attention due to its potential applications in biosensors and medical diagnostics. Here, we report an indirect soft-lithography-mediated method of fabricating hemoglobin (Hb) patterns in the submicrometer length scales region on indium-tin-oxide (ITO). Scanning electron microscopy, quartz crystal microbalance, and cyclic voltammetry studies reveal the formation of a self-assembled monolayer of Hb on an ITO surface. The present approach provides an easy and reliable means for simultaneous and defectless passivation and submicrometer patterning of proteins, thus indicating its potential application in biological assay.
Source Title: Langmuir
ISSN: 07437463
DOI: 10.1021/la991574o
Appears in Collections:Staff Publications

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