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https://doi.org/10.1021/cc7000919
Title: | Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [i]-condensed purines | Authors: | Fu, H. Tan, M.K.C. Lam, Y. |
Issue Date: | Sep-2007 | Citation: | Fu, H., Tan, M.K.C., Lam, Y. (2007-09). Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [i]-condensed purines. Journal of Combinatorial Chemistry 9 (5) : 804-810. ScholarBank@NUS Repository. https://doi.org/10.1021/cc7000919 | Abstract: | A highly regioselective and traceless solid-phase route to 1,7,8-trisubstituted purines has been developed. This methodology could be extended to the preparation of 8-azapurines and [i]-condensed purines. A representative set of 17 purines, azapurines, and [i]-condensed purines was synthesized. This paper also describes a mild method to prepare the p-benzyloxybenzylamine (BOBA) resin. © 2007 American Chemical Society. | Source Title: | Journal of Combinatorial Chemistry | URI: | http://scholarbank.nus.edu.sg/handle/10635/76880 | ISSN: | 15204766 | DOI: | 10.1021/cc7000919 |
Appears in Collections: | Staff Publications |
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