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|Title:||Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [i]-condensed purines||Authors:||Fu, H.
|Issue Date:||Sep-2007||Citation:||Fu, H., Tan, M.K.C., Lam, Y. (2007-09). Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [i]-condensed purines. Journal of Combinatorial Chemistry 9 (5) : 804-810. ScholarBank@NUS Repository. https://doi.org/10.1021/cc7000919||Abstract:||A highly regioselective and traceless solid-phase route to 1,7,8-trisubstituted purines has been developed. This methodology could be extended to the preparation of 8-azapurines and [i]-condensed purines. A representative set of 17 purines, azapurines, and [i]-condensed purines was synthesized. This paper also describes a mild method to prepare the p-benzyloxybenzylamine (BOBA) resin. © 2007 American Chemical Society.||Source Title:||Journal of Combinatorial Chemistry||URI:||http://scholarbank.nus.edu.sg/handle/10635/76880||ISSN:||15204766||DOI:||10.1021/cc7000919|
|Appears in Collections:||Staff Publications|
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