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Title: Peptide microarray for high-throughput determination of phosphatase specificity and biology
Authors: Sun, H.
Lu, C.H.S.
Uttamchandani, M. 
Xia, Y.
Liou, Y.-C. 
Yao, S.Q. 
Keywords: Microarrays
Substrate specificity
Issue Date: 15-Feb-2008
Citation: Sun, H., Lu, C.H.S., Uttamchandani, M., Xia, Y., Liou, Y.-C., Yao, S.Q. (2008-02-15). Peptide microarray for high-throughput determination of phosphatase specificity and biology. Angewandte Chemie - International Edition 47 (9) : 1698-1702. ScholarBank@NUS Repository.
Abstract: Identifying phosphatase substrates: A peptide microarray has been developed for the high-throughput study of Ser/Thr phosphatases. Putative peptide substrates, upon immobilization onto a glass slide, could be used to obtain kinetic information and identify the substrate preferences of a Ser/Thr phosphatase (see schematic representation); with this information, new biology of the enzyme could be discovered. (Figure Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
Source Title: Angewandte Chemie - International Edition
ISSN: 14337851
DOI: 10.1002/anie.200703473
Appears in Collections:Staff Publications

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