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Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol102597s
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dc.titleEnantioselective Morita-Baylis-Hillman reaction of isatins with acrylates: Facile creation of 3-hydroxy-2-oxindoles
dc.contributor.authorZhong, F.
dc.contributor.authorChen, G.-Y.
dc.contributor.authorLu, Y.
dc.date.accessioned2014-06-23T05:38:36Z
dc.date.available2014-06-23T05:38:36Z
dc.date.issued2011-01-07
dc.identifier.citationZhong, F., Chen, G.-Y., Lu, Y. (2011-01-07). Enantioselective Morita-Baylis-Hillman reaction of isatins with acrylates: Facile creation of 3-hydroxy-2-oxindoles. Organic Letters 13 (1) : 82-85. ScholarBank@NUS Repository. https://doi.org/10.1021/ol102597s
dc.identifier.issn15237060
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/76103
dc.description.abstractThe first tertiary amine catalyzed enantioselective Morita-Baylis-Hillman (MBH) reaction of isatins with acrylates has been demonstrated, allowing asymmetric synthesis of biologically significant 3-substituted-3-hydroxy-2- oxindoles in good yields and with excellent enantioselectivities. The C6′-OH group of β-isocupreidine (β-ICD) is believed to facilitate the key proton transfer step in the MBH reaction, via an intramolecular proton relay process. © 2010 American Chemical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/ol102597s
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1021/ol102597s
dc.description.sourcetitleOrganic Letters
dc.description.volume13
dc.description.issue1
dc.description.page82-85
dc.identifier.isiut000285728000022
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