Please use this identifier to cite or link to this item: https://doi.org/10.1007/BF00123408
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dc.titleDimethyl sulfoxide as an anticalcification agent for glutaraldehyde-fixed biological tissue
dc.contributor.authorKhor, E.
dc.contributor.authorWee, A.
dc.contributor.authorLoke, W.K.
dc.contributor.authorTan, B.L.
dc.date.accessioned2014-06-23T05:36:36Z
dc.date.available2014-06-23T05:36:36Z
dc.date.issued1996-11
dc.identifier.citationKhor, E., Wee, A., Loke, W.K., Tan, B.L. (1996-11). Dimethyl sulfoxide as an anticalcification agent for glutaraldehyde-fixed biological tissue. Journal of Materials Science: Materials in Medicine 7 (11) : 691-693. ScholarBank@NUS Repository. https://doi.org/10.1007/BF00123408
dc.identifier.issn09574530
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/75943
dc.description.abstractDimethylsulfoxide has been found to mitigate the calcification of glutaraldehyde-fixed biological tissue in the rat subdermal model. This effect is achieved with neat dimethylsulfoxide either prior to or after glutaraldehyde fixation of the biological tissue. The calcium levels for the 21 days post-implant for both methods are over 20 times less than the controls. However, fixation of the tissue with glutaraldehyde before dimethylsulfoxide treatment appears to better control calcification over the longer term. Histological examination of samples after exposure before or after implantation show no deleterious effects to the tissue due to dimethylsulfoxide.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/BF00123408
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1007/BF00123408
dc.description.sourcetitleJournal of Materials Science: Materials in Medicine
dc.description.volume7
dc.description.issue11
dc.description.page691-693
dc.description.codenJSMME
dc.identifier.isiutA1996VR24100007
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