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Please use this identifier to cite or link to this item: https://doi.org/10.1039/c000283f
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dc.titleAn unnatural amino acid that mimics phosphotyrosine
dc.contributor.authorGe, J.
dc.contributor.authorWu, H.
dc.contributor.authorYao, S.Q.
dc.date.accessioned2014-06-23T05:31:57Z
dc.date.available2014-06-23T05:31:57Z
dc.date.issued2010
dc.identifier.citationGe, J., Wu, H., Yao, S.Q. (2010). An unnatural amino acid that mimics phosphotyrosine. Chemical Communications 46 (17) : 2980-2982. ScholarBank@NUS Repository. https://doi.org/10.1039/c000283f
dc.identifier.issn13597345
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/75570
dc.description.abstractBy replacing the phosphate group in pTyr with an isoxazole carboxylic acid, a novel unnatural amino acid has been successfully synthesized. Subsequently, its incorporation into a known PPI (protein-protein interaction) inhibitor of STAT3 protein (ISS 610) generated I2 which showed reasonable anti-STAT3 activity in both fluorescence polarization and cell-proliferation experiments. © The Royal Society of Chemistry 2010.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c000283f
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1039/c000283f
dc.description.sourcetitleChemical Communications
dc.description.volume46
dc.description.issue17
dc.description.page2980-2982
dc.description.codenCHCOF
dc.identifier.isiut000276632800028
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