Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tet.2010.11.075
Title: A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2- ones and thiones
Authors: Fang, Z.
Lam, Y. 
Keywords: Biginelli reaction
Chemoselectivity
Cyclocondensation
Microwave reaction
Multicomponent reaction
Issue Date: 11-Feb-2011
Citation: Fang, Z., Lam, Y. (2011-02-11). A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2- ones and thiones. Tetrahedron 67 (6) : 1294-1297. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tet.2010.11.075
Abstract: A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2- ones and thiones was developed. The reaction involves a one-pot reaction between oxalacetic acid, thiourea/urea, and aldehyde under microwave irradiation and provides the products in good yields and much shorter reaction times. © 2010 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron
URI: http://scholarbank.nus.edu.sg/handle/10635/75477
ISSN: 00404020
DOI: 10.1016/j.tet.2010.11.075
Appears in Collections:Staff Publications

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