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https://doi.org/10.1016/j.tet.2010.11.075
Title: | A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2- ones and thiones | Authors: | Fang, Z. Lam, Y. |
Keywords: | Biginelli reaction Chemoselectivity Cyclocondensation Microwave reaction Multicomponent reaction |
Issue Date: | 11-Feb-2011 | Citation: | Fang, Z., Lam, Y. (2011-02-11). A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2- ones and thiones. Tetrahedron 67 (6) : 1294-1297. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tet.2010.11.075 | Abstract: | A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2- ones and thiones was developed. The reaction involves a one-pot reaction between oxalacetic acid, thiourea/urea, and aldehyde under microwave irradiation and provides the products in good yields and much shorter reaction times. © 2010 Elsevier Ltd. All rights reserved. | Source Title: | Tetrahedron | URI: | http://scholarbank.nus.edu.sg/handle/10635/75477 | ISSN: | 00404020 | DOI: | 10.1016/j.tet.2010.11.075 |
Appears in Collections: | Staff Publications |
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