Please use this identifier to cite or link to this item:
Title: Technology development to explore the relationship between oral health and the oral microbial community
Authors: Starke, E.M.L.
Smoot, J.C.
Smoot, L.M.
Liu, W.-T. 
Chandler, D.P.
Lee, H.H.
Stahl, D.A.
Issue Date: 2006
Citation: Starke, E.M.L.,Smoot, J.C.,Smoot, L.M.,Liu, W.-T.,Chandler, D.P.,Lee, H.H.,Stahl, D.A. (2006). Technology development to explore the relationship between oral health and the oral microbial community. BMC Oral Health 6 (SUPPL. 1) : -. ScholarBank@NUS Repository.
Abstract: The human oral cavity contains a complex microbial community that, until recently, has not been well characterized. Studies using molecular tools have begun to enumerate and quantify the species residing in various niches of the oral cavity; yet, virtually every study has revealed additional new species, and little is known about the structural dynamics of the oral microbial community or how it changes with disease. Current estimates of bacterial diversity in the oral cavity range up to 700 species, although in any single individual this number is much lower. Oral microbes are responsible for common chronic diseases and are suggested to be sentinels of systemic human diseases. Microarrays are now being used to study oral microbiota in a systematic and robust manner. Although this technology is still relatively young, improvements have been made in all aspects of the technology, including advances that provide better discrimination between perfect-match hybridizations from non-specific (and closely-related) hybridizations. This review addresses a core technology using gel-based microarrays and the initial integration of this technology into a single device needed for system-wide studies of complex microbial community structure and for the development of oral diagnostic devices. © 2006 Starke et al.; licensee BioMed Central Ltd.
Source Title: BMC Oral Health
ISSN: 14726831
DOI: 10.1186/1472-6831-6-S1-S10
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.


checked on Oct 20, 2019

Page view(s)

checked on Oct 13, 2019

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.