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https://doi.org/10.1002/(SICI)1097-4636(19980915)41:4<541
Title: | Preparation of a chitin-apatite composite by in situ precipitation onto porous chitin scaffolds | Authors: | Wan, A.C.A. Khor, E. Hastings, G.W. |
Keywords: | Apatite Chitin Hydroxyaparite In situ precipitation |
Issue Date: | 15-Sep-1998 | Citation: | Wan, A.C.A., Khor, E., Hastings, G.W. (1998-09-15). Preparation of a chitin-apatite composite by in situ precipitation onto porous chitin scaffolds. Journal of Biomedical Materials Research 41 (4) : 541-548. ScholarBank@NUS Repository. https://doi.org/10.1002/(SICI)1097-4636(19980915)41:4<541 | Abstract: | Composites of chitin with calcium phosphate were obtained by in situ precipitation of the mineral from a supersaturated solution onto chitin scaffolds. The chitin scaffolds were obtained by freeze drying to give a highly porous structure possessing a polar surface favorable for apatite nucleation and growth. The extent and arrangement of calcium phosphate deposits on the chitin and substituted chitin scaffolds were explored. Up to 55% by mass of calcium phosphate could be incorporated into chitin scaffolds. Deposits on the chitin surface were of a continuous apatite carpet nature while deposits on carboxymethylated chitin surfaces displayed a spherical morphology. Carboxymethylation of chitin exerts an overall inhibitory effect towards calcium phosphate deposition, but it provides for site-specific nucleation of the mineral phase. In situ precipitation can be an important route in the future production of various polymer-calcium phosphate composites. | Source Title: | Journal of Biomedical Materials Research | URI: | http://scholarbank.nus.edu.sg/handle/10635/75070 | ISSN: | 00219304 | DOI: | 10.1002/(SICI)1097-4636(19980915)41:4<541 |
Appears in Collections: | Staff Publications |
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