Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/74822
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dc.titleAbsorption effects in optical coherence tomography modeling
dc.contributor.authorChow, T.H.
dc.contributor.authorKah, J.C.Y.
dc.contributor.authorTan, K.M.
dc.contributor.authorNg, B.K.
dc.contributor.authorGulam, R.S.
dc.contributor.authorSheppard, C.J.R.
dc.date.accessioned2014-06-19T08:57:53Z
dc.date.available2014-06-19T08:57:53Z
dc.date.issued2007
dc.identifier.citationChow, T.H.,Kah, J.C.Y.,Tan, K.M.,Ng, B.K.,Gulam, R.S.,Sheppard, C.J.R. (2007). Absorption effects in optical coherence tomography modeling. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6627 : -. ScholarBank@NUS Repository.
dc.identifier.isbn0819467715
dc.identifier.issn16057422
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/74822
dc.description.abstractEstimation of the tissue optical characteristics using optical coherence tomography (OCT) requires good modeling. Present modeling of the system includes effects such as scattering of light in tissues. However, absorption effects were often neglected in the model. They may be significant depending on the tissue type and the wavelength of the light source. We present a study where the effects of absorption in light propagation in biological tissue were examined in the theoretical modeling of OCT based on the single-scattering model. OCT M-scans were performed on liquid tissue phantoms at 1% concentration. In order to mimic the effects of absorption, India ink was added to the solution. Different concentrations of Indian ink were used to vary the absorption coefficient in the tissue phantoms. Estimation of the absorption, scattering coefficients from the OCT signal were obtained. Substantial reduction in the slope of the logarithmic OCT signal was observed when India ink was introduced to the liquid tissue phantoms. The results suggest that the effects of the absorption clearly affected the estimation of the overall extinction coefficient. In order to improve the accuracy of estimation of these characteristics, absorption effects should be taken into account. © 2007 SPIE-OSA.
dc.sourceScopus
dc.subjectAbsorption coefficient
dc.subjectOptical coherence tomography
dc.subjectScattering coefficient
dc.subjectTissue phantom
dc.typeConference Paper
dc.contributor.departmentBIOENGINEERING
dc.description.sourcetitleProgress in Biomedical Optics and Imaging - Proceedings of SPIE
dc.description.volume6627
dc.description.page-
dc.identifier.isiutNOT_IN_WOS
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