Please use this identifier to cite or link to this item: https://doi.org/10.1007/978-3-540-69139-6-206
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dc.titleA novel trypsin-like serine proteinase from the venom of the Chinese scorpion Buthus martensii Karsch
dc.contributor.authorGao, R.
dc.contributor.authorZhang, Y.
dc.contributor.authorGopalakrishnakone, P.
dc.date.accessioned2014-06-19T08:57:52Z
dc.date.available2014-06-19T08:57:52Z
dc.date.issued2008
dc.identifier.citationGao, R.,Zhang, Y.,Gopalakrishnakone, P. (2008). A novel trypsin-like serine proteinase from the venom of the Chinese scorpion Buthus martensii Karsch. IFMBE Proceedings 21 IFMBE (1) : 829-832. ScholarBank@NUS Repository. <a href="https://doi.org/10.1007/978-3-540-69139-6-206" target="_blank">https://doi.org/10.1007/978-3-540-69139-6-206</a>
dc.identifier.isbn9783540691389
dc.identifier.issn16800737
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/74820
dc.description.abstractBy using the combination of gel filtration, ion-exchange and reveres-phase chromatography, a novel trypsinlike serine proteinase was isolated from the venom of Buthus martensii Karsch and named BMK-CB. The apparent molecular weight of BMK-CB was identified as 32 kDa by SDSPAGE. The N-terminal sequence of 40 amino acids was obtained by Edman degradation. The sequence shows highest similarity to proteinase from insect source. The purified BMKCB was found to bind to the cancer cell line MCF-7 and the cell binding ability was dose-dependent. To our knowledge, BMK-CB forms the first trypsin-like serine proteinase from the scorpion venom. © 2008 Springer-Verlag.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/978-3-540-69139-6-206
dc.sourceScopus
dc.subjectCell binding
dc.subjectPurification
dc.subjectScorpion venom
dc.subjectSerine proteinase
dc.typeConference Paper
dc.contributor.departmentNUS NANOSCIENCE & NANOTECH INITIATIVE
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1007/978-3-540-69139-6-206
dc.description.sourcetitleIFMBE Proceedings
dc.description.volume21 IFMBE
dc.description.issue1
dc.description.page829-832
dc.identifier.isiutNOT_IN_WOS
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