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https://doi.org/10.1109/IJCBS.2009.94
Title: | Automaton models of computational genetic regulatory networks with combinatorial gene-protein logical interactions | Authors: | Chen, P.C.Y. Weng, Y. |
Keywords: | Automata Combinatorial logic Gene networks |
Issue Date: | 2009 | Citation: | Chen, P.C.Y., Weng, Y. (2009). Automaton models of computational genetic regulatory networks with combinatorial gene-protein logical interactions. Proceedings - 2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing, IJCBS 2009 : 301-307. ScholarBank@NUS Repository. https://doi.org/10.1109/IJCBS.2009.94 | Abstract: | This article presents a formal framework for modeling computational genetic regulatory networks as automata, with multi-threshold protein concentration and combinatorial logical gene-protein interactions. By computing the intersection of the languages generated by these automata we obtain the complete set of pathways in a gene network. We illustrate the effectiveness of our framework in the modeling of (i) morphogenesis in Arabidopsis and (ii) regulation in phage λ. © 2009 IEEE. | Source Title: | Proceedings - 2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing, IJCBS 2009 | URI: | http://scholarbank.nus.edu.sg/handle/10635/73215 | ISBN: | 9780769537399 | DOI: | 10.1109/IJCBS.2009.94 |
Appears in Collections: | Staff Publications |
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