Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/68278
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dc.titleInterface tissue engineering: Next phase in musculoskeletal tissue repair
dc.contributor.authorSahoo, S.
dc.contributor.authorTeh, T.K.
dc.contributor.authorHe, P.
dc.contributor.authorToh, S.L.
dc.contributor.authorGoh, J.C.
dc.date.accessioned2014-06-18T06:11:37Z
dc.date.available2014-06-18T06:11:37Z
dc.date.issued2011-05
dc.identifier.citationSahoo, S.,Teh, T.K.,He, P.,Toh, S.L.,Goh, J.C. (2011-05). Interface tissue engineering: Next phase in musculoskeletal tissue repair. Annals of the Academy of Medicine Singapore 40 (5) : 246-251. ScholarBank@NUS Repository.
dc.identifier.issn03044602
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/68278
dc.description.abstractIncreasing incidence of musculoskeletal injuries coupled with limitations in the current treatment options have necessitated tissue engineering and regenerative medicine- based approaches. Moving forward from engineering isolated musculoskeletal tissues, research strategies are now being increasingly focused on repairing and regenerating the interfaces between dissimilar musculoskeletal tissues with the aim to achieve seamless integration of engineered musculoskeletal tissues. This article reviews the state-of-the-art in the tissue engineering of musculoskeletal tissue interfaces with a focus on Singapore's contribution in this emerging field. Various biomimetic scaffold and cellbased strategies, the use of growth factors, gene therapy and mechanical loading, as well as animal models for functional validation of the tissue engineering strategies are discussed.
dc.sourceScopus
dc.subjectFunctional tissue engineering
dc.subjectOrthopaedic interfaces
dc.subjectRegenerative medicine
dc.subjectScaffolds
dc.typeReview
dc.contributor.departmentBIOENGINEERING
dc.contributor.departmentORTHOPAEDIC SURGERY
dc.description.sourcetitleAnnals of the Academy of Medicine Singapore
dc.description.volume40
dc.description.issue5
dc.description.page246-251
dc.description.codenAAMSC
dc.identifier.isiutNOT_IN_WOS
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