Please use this identifier to cite or link to this item:
|Title:||Fabricating tissue engineering scaffolds for simultaneous cell growth and drug delivery||Authors:||Chen, W.
Tissue engineering scaffold
|Issue Date:||2010||Citation:||Chen, W., Tabata, Y., Tong, Y.W. (2010). Fabricating tissue engineering scaffolds for simultaneous cell growth and drug delivery. Current Pharmaceutical Design 16 (21) : 2388-2394. ScholarBank@NUS Repository. https://doi.org/10.2174/138161210791920478||Abstract:||The formulation and fabrication methods for several types of tissue engineering scaffolds with drug delivery capabilities are presented in this review. Tissue engineered constructs are temporary substitutes developed to treat damaged or lost tissue. One key component of such constructs is scaffolds that are often developed to mimic the extra cellular matrix (ECM). As natural ECM contains biomolecules to support proper growth and function of cells, inclusion of these biomolecular cues have been shown to be necessary for proper cell growth and function in tissue engineering. Thus, an effective tissue engineering scaffold should provide such biomolecular cues. This can be achieved through drug delivery in scaffolds. Studies have shown that drug delivery systems are necessary to protect drugs, and provide sustained drug release that is often needed for effective therapy. The tissue engineering features of 4 scaffold types are described, including films, hydrogels, fibers, and microspheres/nanospheres. Fabrication techniques and drug encapsulation methods for these scaffolds are reviewed in addition to some observations arising from the use of these techniques and methods. © 2010 Bentham Science Publishers Ltd.||Source Title:||Current Pharmaceutical Design||URI:||http://scholarbank.nus.edu.sg/handle/10635/68240||ISSN:||13816128||DOI:||10.2174/138161210791920478|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Aug 15, 2019
WEB OF SCIENCETM
checked on Aug 8, 2019
checked on Aug 18, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.