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Title: Bioactive surfaces and biomaterials via atom transfer radical polymerization
Authors: Xu, F.J. 
Neoh, K.G. 
Kang, E.T. 
Keywords: ATRP
Bioactive surfaces
Biomedical applications
Issue Date: Aug-2009
Citation: Xu, F.J., Neoh, K.G., Kang, E.T. (2009-08). Bioactive surfaces and biomaterials via atom transfer radical polymerization. Progress in Polymer Science (Oxford) 34 (8) : 719-761. ScholarBank@NUS Repository.
Abstract: Recent progress in controlled radical polymerizations, in particular atom transfer radical polymerization (ATRP), has provided a unique means for the design and synthesis of bioactive surfaces and functional biomaterials. This review summarizes such recent research activities. The synthesis strategies of bioactive surfaces and biomaterials via ATRP are described in detail. The highly robust and versatile ATRP technique is particularly suited for the preparation of functional bioactive surfaces, including antifouling, antibacterial, stimuli-responsive, biomolecule-coupled and micropatterned surfaces. In addition to bioactive surfaces, ATRP has also been widely used for the preparation of well-structured functional biomaterials, such as micellar delivery systems, hydrogels, cationic gene carriers and polymer-protein conjugates. The research activities in the last decade indicate that ATRP has become an essential tool for the design and synthesis of advanced, noble and novel biomaterials. © 2009 Elsevier Ltd. All rights reserved.
Source Title: Progress in Polymer Science (Oxford)
ISSN: 00796700
DOI: 10.1016/j.progpolymsci.2009.04.005
Appears in Collections:Staff Publications

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