Please use this identifier to cite or link to this item: https://doi.org/10.1063/1.2902298
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dc.titleHeterodyne polarization coherent anti-Stokes Raman scattering microscopy
dc.contributor.authorLu, F.
dc.contributor.authorZheng, W.
dc.contributor.authorHuang, Z.
dc.date.accessioned2014-06-17T09:44:12Z
dc.date.available2014-06-17T09:44:12Z
dc.date.issued2008
dc.identifier.citationLu, F., Zheng, W., Huang, Z. (2008). Heterodyne polarization coherent anti-Stokes Raman scattering microscopy. Applied Physics Letters 92 (12) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.2902298
dc.identifier.issn00036951
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/67081
dc.description.abstractWe develop a heterodyne-detected polarization coherent anti-Stokes Raman scattering (HP-CARS) microscopy for high sensitive and high contrast molecular vibration imaging. The HP-CARS technique, which utilizes interference of the weak resonant CARS signal and the relatively intense local oscillator field generated simultaneously within the same focal excitation volume of the sample for optical heterodyne detection, yields an approximately sevenfold improvement in vibrational contrast compared with local oscillator CARS, while exhibiting a 12-fold amplification of the resonant signal compared with P-CARS. We demonstrate this method by imaging both 4.69 μm polystyrene beads and unstained human epithelial cells in aqueous environments. © 2008 American Institute of Physics.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1063/1.2902298
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1063/1.2902298
dc.description.sourcetitleApplied Physics Letters
dc.description.volume92
dc.description.issue12
dc.description.page-
dc.description.codenAPPLA
dc.identifier.isiut000254510300101
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