Please use this identifier to cite or link to this item: https://doi.org/10.1088/0031-9155/53/4/008
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dc.titleBeveled fiber-optic probe couples a ball lens for improving depth-resolved fluorescence measurements of layered tissue: Monte Carlo simulations
dc.contributor.authorJaillon, F.
dc.contributor.authorZheng, W.
dc.contributor.authorHuang, Z.
dc.date.accessioned2014-06-17T09:42:31Z
dc.date.available2014-06-17T09:42:31Z
dc.date.issued2008
dc.identifier.citationJaillon, F., Zheng, W., Huang, Z. (2008). Beveled fiber-optic probe couples a ball lens for improving depth-resolved fluorescence measurements of layered tissue: Monte Carlo simulations. Physics in Medicine and Biology 53 (4) : 937-951. ScholarBank@NUS Repository. https://doi.org/10.1088/0031-9155/53/4/008
dc.identifier.issn00319155
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/66942
dc.description.abstractIn this study, we evaluate the feasibility of designing a beveled fiber-optic probe coupled with a ball lens for improving depth-resolved fluorescence measurements of epithelial tissue using Monte Carlo (MC) simulations. The results show that by using the probe configuration with a beveled tip collection fiber and a flat tip excitation fiber associated with a ball lens, discrimination of fluorescence signals generated in different tissue depths is achievable. In comparison with a flat-tip collection fiber, the use of a large bevel angled collection fiber enables a better differentiation between the shallow and deep tissue layers by changing the excitation-collection fiber separations. This work suggests that the beveled fiber-optic probe coupled with a ball lens has the potential to facilitate depth-resolved fluorescence measurements of epithelial tissues. © 2008 Institute of Physics and Engineering in Medicine.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1088/0031-9155/53/4/008
dc.description.sourcetitlePhysics in Medicine and Biology
dc.description.volume53
dc.description.issue4
dc.description.page937-951
dc.description.codenPHMBA
dc.identifier.isiut000254175400009
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