Please use this identifier to cite or link to this item:
|Title:||Silica nanocapsules of fluorescent conjugated polymers and superparamagnetic nanocrystals for dual-mode cellular imaging||Authors:||Tan, H.
|Issue Date:||6-Jun-2011||Citation:||Tan, H., Wang, M., Yang, C.-T., Pant, S., Bhakoo, K.K., Wong, S.Y., Chen, Z.-K., Li, X., Wang, J. (2011-06-06). Silica nanocapsules of fluorescent conjugated polymers and superparamagnetic nanocrystals for dual-mode cellular imaging. Chemistry - A European Journal 17 (24) : 6696-6706. ScholarBank@NUS Repository.||Abstract:||We describe here a facile and benign synthetic strategy to integrate the fluorescent behavior of conjugated polymers and superparamagnetic properties of iron oxide nanocrystals into silica nanocapsules, forming a new type of bifunctional magnetic fluorescent silica nanocapsule (BMFSN). The resultant BMFSNs are uniform, colloidally stable in aqueous medium, and exhibit the desired dual functionality of fluorescence and superparamagnetism in a single entity. Four conjugated polymers with different emissions were used to demonstrate the versatility of employing this class of fluorescent materials for the preparation of BMFSNs. The applicability of BMFSNs in cellular imaging was studied by incubating them with human liver cancer cells, the result of which demonstrated that the cells could be visualized by dual-mode fluorescence and magnetic resonance imaging. Furthermore, the superparamagnetic behavior of the BMFSNs was exploited for in vitro magnetic-guided delivery of the nanocapsules into the cancer cells, thereby highlighting their potential for targeting biomedical applications. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.||Source Title:||Chemistry - A European Journal||URI:||http://scholarbank.nus.edu.sg/handle/10635/64996||ISSN:||09476539|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 6, 2018
WEB OF SCIENCETM
checked on Oct 1, 2021
checked on May 26, 2022
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.