Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.tet.2010.06.039
DC Field | Value | |
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dc.title | Highly chemo- and regio-selective hydroxylations of o- and m-substituted toluenes to benzyl alcohols with Cellulosimicrobium cellulans EB-8-4 | |
dc.contributor.author | Dai, S. | |
dc.contributor.author | Wu, J. | |
dc.contributor.author | Wang, Z. | |
dc.contributor.author | Chen, Y. | |
dc.contributor.author | Li, Z. | |
dc.date.accessioned | 2014-06-17T07:42:20Z | |
dc.date.available | 2014-06-17T07:42:20Z | |
dc.date.issued | 2010-08-21 | |
dc.identifier.citation | Dai, S., Wu, J., Wang, Z., Chen, Y., Li, Z. (2010-08-21). Highly chemo- and regio-selective hydroxylations of o- and m-substituted toluenes to benzyl alcohols with Cellulosimicrobium cellulans EB-8-4. Tetrahedron 66 (34) : 6919-6923. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tet.2010.06.039 | |
dc.identifier.issn | 00404020 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/64022 | |
dc.description.abstract | Highly chemo- and regio-selective benzylic hydroxylations of o- and m-substituted toluenes were achieved with the easily available and easy-to-handle resting cells of Cellulosimicrobium cellulans EB-8-4 as biocatalysts, giving the corresponding benzyl alcohols as single product. Benzyl alcohols were obtained in 78-94% yield, demonstrating the first green, clean, and simple method for the preparation of benzyl alcohols via hydroxylations. Biotransformation of 4-methylbenzyl chloride with the same strain gave 4-methylbenzyl alcohol in 67-81% yield, suggesting a novel dehalogenation activity of the cells and providing a novel, green, and efficient method for the preparation of 4-methylbenzyl alcohol as well as the application potential in biodegradation of chlorine-containing aromatics. © 2010 Elsevier Ltd. All rights reserved. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.tet.2010.06.039 | |
dc.source | Scopus | |
dc.subject | Alkyl toluenes | |
dc.subject | Benzyl alcohols | |
dc.subject | Biotransformations | |
dc.subject | Enzyme catalysis | |
dc.subject | Hydroxylations | |
dc.type | Article | |
dc.contributor.department | CHEMICAL & BIOMOLECULAR ENGINEERING | |
dc.description.doi | 10.1016/j.tet.2010.06.039 | |
dc.description.sourcetitle | Tetrahedron | |
dc.description.volume | 66 | |
dc.description.issue | 34 | |
dc.description.page | 6919-6923 | |
dc.description.coden | TETRA | |
dc.identifier.isiut | 000280953500033 | |
Appears in Collections: | Staff Publications |
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