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https://doi.org/10.1002/smll.201201363
| Title: | Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes | Authors: | Zhao, Y. Howe, J.L.C. Yu, Z. Leong, D.T. Chu, J.J.H. Loo, J.S.C. Ng, K.W. |
Keywords: | autophagy keratinocytes nanoparticles nanotoxicology titanium dioxide |
Issue Date: | 11-Feb-2013 | Citation: | Zhao, Y., Howe, J.L.C., Yu, Z., Leong, D.T., Chu, J.J.H., Loo, J.S.C., Ng, K.W. (2013-02-11). Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes. Small 9 (3) : 387-392. ScholarBank@NUS Repository. https://doi.org/10.1002/smll.201201363 | Abstract: | Understanding the mechanisms of cell-nanomaterial interactions is vital in harnessing the potential of using nanomaterials in biomedical applications. By immuno-labeling of LC3 and TEM analysis, it is found that titanium dioxide nanoparticles are internalized by human keratinocytes and induce autophagy. Autophagy appears to play a cytoprotective role in response to toxicity influence exerted by the nanoparticles. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Source Title: | Small | URI: | http://scholarbank.nus.edu.sg/handle/10635/63897 | ISSN: | 16136810 | DOI: | 10.1002/smll.201201363 |
| Appears in Collections: | Staff Publications |
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