Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes

Please use this identifier to cite or link to this item: https://doi.org/10.1002/smll.201201363

Title:	Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes
Authors:	Zhao, Y. Howe, J.L.C. Yu, Z. Leong, D.T. Chu, J.J.H. Loo, J.S.C. Ng, K.W.
Keywords:	autophagy keratinocytes nanoparticles nanotoxicology titanium dioxide
Issue Date:	11-Feb-2013
Citation:	Zhao, Y., Howe, J.L.C., Yu, Z., Leong, D.T., Chu, J.J.H., Loo, J.S.C., Ng, K.W. (2013-02-11). Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes. Small 9 (3) : 387-392. ScholarBank@NUS Repository. https://doi.org/10.1002/smll.201201363
Abstract:	Understanding the mechanisms of cell-nanomaterial interactions is vital in harnessing the potential of using nanomaterials in biomedical applications. By immuno-labeling of LC3 and TEM analysis, it is found that titanium dioxide nanoparticles are internalized by human keratinocytes and induce autophagy. Autophagy appears to play a cytoprotective role in response to toxicity influence exerted by the nanoparticles. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title:	Small
URI:	http://scholarbank.nus.edu.sg/handle/10635/63897
ISSN:	16136810
DOI:	10.1002/smll.201201363
Appears in Collections:	Staff Publications

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