Please use this identifier to cite or link to this item: https://doi.org/10.1039/c0nr00950d
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dc.titleConjugated polyelectrolyte-cisplatin complex nanoparticles for simultaneous in vivo imaging and drug tracking
dc.contributor.authorDing, D.
dc.contributor.authorLi, K.
dc.contributor.authorZhu, Z.
dc.contributor.authorPu, K.-Y.
dc.contributor.authorHu, Y.
dc.contributor.authorJiang, X.
dc.contributor.authorLiu, B.
dc.date.accessioned2014-06-17T07:37:51Z
dc.date.available2014-06-17T07:37:51Z
dc.date.issued2011-05
dc.identifier.citationDing, D., Li, K., Zhu, Z., Pu, K.-Y., Hu, Y., Jiang, X., Liu, B. (2011-05). Conjugated polyelectrolyte-cisplatin complex nanoparticles for simultaneous in vivo imaging and drug tracking. Nanoscale 3 (5) : 1997-2002. ScholarBank@NUS Repository. https://doi.org/10.1039/c0nr00950d
dc.identifier.issn20403364
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/63642
dc.description.abstractA molecular brush based on conjugated polyelectrolyte (CPE) grafted with dense poly(ethylene glycol) (PEG) chains was successfully complexed with an anticancer agent, cisplatin, to form cisplatin-loaded nanoparticles (CPE-PEG-Pt). The obtained nanoparticles have high far-red/near-infrared fluorescence and are able to release the drug in a continuous and slow manner. These nanoparticles have not only been used to visualize HepG2 cancer cells, but also served as an in vivo fluorescent imaging probe that simultaneously tracks the in vivo drug distribution in nude mice upon intravenous administration. © 2011 The Royal Society of Chemistry.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c0nr00950d
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMICAL & BIOMOLECULAR ENGINEERING
dc.description.doi10.1039/c0nr00950d
dc.description.sourcetitleNanoscale
dc.description.volume3
dc.description.issue5
dc.description.page1997-2002
dc.identifier.isiut000290531500010
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