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Title: Bioactive titanium implant surfaces with bacterial inhibition and osteoblast function enhancement properties
Authors: Shi, Z.L. 
Chua, P.H.
Neoh, K.G. 
Kang, E.T. 
Wang, W.
Keywords: Antibacterial
Implant-associated infections
Surface modification
Issue Date: Sep-2008
Citation: Shi, Z.L.,Chua, P.H.,Neoh, K.G.,Kang, E.T.,Wang, W. (2008-09). Bioactive titanium implant surfaces with bacterial inhibition and osteoblast function enhancement properties. International Journal of Artificial Organs 31 (9) : 777-785. ScholarBank@NUS Repository.
Abstract: Infection in orthopedic implant surgery is a serious complication and a major cause of implant failure. Upon implant insertion, a contest between microbial colonization and tissue integration of the implant surface ensues. This race for the surface determines the probability of tissue integration or infection, and the surface properties of the substrate have an important role to play in determining the outcome. A number of strategies have been developed for the modification of implant surfaces to promote bone cell (osteoblast) functions and inhibit bacterial adhesion and growth. In this article, a review is given of these surface modification strategies, in particular those which can achieve the dual aim of bacterial inhibition and simultaneous enhancement of osteoblast functions. Surfaces of these types can be expected to have excellent potential for orthopedic applications. © Wichtig Editore, 2008.
Source Title: International Journal of Artificial Organs
ISSN: 03913988
Appears in Collections:Staff Publications

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