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|Title:||Pulsatile flow studies of a porcine bioprosthetic aortic valve in vitro: PIV measurements and shear-induced blood damage||Authors:||Lim, W.L
Particle image velocimetry
Porcine bioprosthetic valve
|Issue Date:||2001||Citation:||Lim, W.L, Chew, Y.T, Chew, T.C, Low, H.T (2001). Pulsatile flow studies of a porcine bioprosthetic aortic valve in vitro: PIV measurements and shear-induced blood damage. Journal of Biomechanics 34 (11) : 1417-1427. ScholarBank@NUS Repository. https://doi.org/10.1016/S0021-9290(01)00132-4||Abstract:||A two-dimensional particle image tracking velocimetry (PIV) system has been used to map the velocity vector fields and Reynolds stresses in the immediate downstream vicinity of a porcine bioprosthetic heart valve at the aortic root region in vitro under pulsatile flow conditions. Measurements were performed at five different time steps of the systolic phase of the cardiac cycle. The velocity vector fields and Reynolds stress mappings at different time steps allowed us to chart a time history of the stress levels experienced by fluid particles as they move across the aortic root. This Lagrangian description of the stresses experienced by individual blood cells enabled us to estimate the propensity of shear-induced damage to platelets and red blood cells. Coupled with flow visualization techniques, the hydrodynamic consequences of introducing a porcine bioprosthetic heart valve into the aortic root was examined. Although the PIV measurements may lack the accuracy of single point measuring systems, the overall view of the flow in the aortic root region compensates for the shortcoming. Copyright © 2001 Elsevier Science Ltd.||Source Title:||Journal of Biomechanics||URI:||http://scholarbank.nus.edu.sg/handle/10635/61175||ISSN:||00219290||DOI:||10.1016/S0021-9290(01)00132-4|
|Appears in Collections:||Staff Publications|
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