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Title: Effect of membrane permeability on capsule substrate adhesion: Computation using immersed interface method
Authors: Jayathilake, P.G. 
Khoo, B.C. 
Tan, Z. 
Keywords: Capsule-substrate adhesion
Fluid mechanics
Fully permeable
Immersed interface method
Issue Date: 2010
Citation: Jayathilake, P.G., Khoo, B.C., Tan, Z. (2010). Effect of membrane permeability on capsule substrate adhesion: Computation using immersed interface method. Chemical Engineering Science 65 (11) : 3567-3578. ScholarBank@NUS Repository.
Abstract: A two-dimensional thin-walled capsule of a flexible permeable membrane is adhered onto a rigid planar substrate under adhesive forces (derived from a potential function). The capsule and the surrounding environment are filled with a diluted binary solution of different solute concentrations. The Stokes flow problem is solved by the immersed interface method (IIM) with equal viscosities for enclosed and surrounding fluid of the capsule. The numerical results obtained are verified against two simplified theoretical solutions with reasonable concurrence. The osmotic inflation of the adhered capsule is studied systematically as a function of solute concentration field and the membrane permeability properties. Our findings indicate that contact length shrinks in dimension and deformation decreases as capsule inflates. Also the equilibrium contact length does not depend on the hydraulic conductivity of the membrane as theoretically expected. Further numerical investigations show that the inflation and detachment of the initially adhered capsule depend significantly on the solute diffusive permeability and the reflection coefficient of capsule membrane. © 2010 Elsevier Ltd. All rights reserved.
Source Title: Chemical Engineering Science
ISSN: 00092509
DOI: 10.1016/j.ces.2010.02.050
Appears in Collections:Staff Publications

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