Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/58454
DC FieldValue
dc.titleMeasurement of respiratory airway-resistance by flow interruption method
dc.contributor.authorLow, H.T.
dc.contributor.authorChew, Y.T.
dc.contributor.authorLim, T.K.
dc.contributor.authorChin, R.
dc.date.accessioned2014-06-17T05:14:45Z
dc.date.available2014-06-17T05:14:45Z
dc.date.issued1991
dc.identifier.citationLow, H.T.,Chew, Y.T.,Lim, T.K.,Chin, R. (1991). Measurement of respiratory airway-resistance by flow interruption method. Annals of Biomedical Engineering 19 (5) : 586-. ScholarBank@NUS Repository.
dc.identifier.issn00906964
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/58454
dc.description.abstractThe interrupter method, commonly used in lung ventilators, assumes that the sudden pressure change upon occlusion at the mouth is equal to the trachea-alveolar pressure-difference before occlusion. The objective of this study is to evaluate the accuracy of the interrupter method by comparison with invasive pressure-flow measurements. Also of interest will be the effect of the shutter closure-speed, breathing direction and breathing frequency. The investigation will be conducted on a simulated respiratory system based on a six-generation hollow-lung model. Measurements have been made of trachea and alveolar pressures, and flow during unassisted breathing, at 0.5 to 3 Hz, and ventilator assisted breathing, at 0.5 to 1 Hz. The pressure and flow are in phase, which supports the quasi-steady assumption. The instantaneous airway-resistance, during unassisted breathing, varies greatly between the inspiratory and expiratory phases. However, an average value could be obtained from the slope of the pressure-flow plot. The airway resistance decreases slightly at higher breathing frequency. The airway resistance obtained during ventilator-assisted breathing compares resonably well with that from the invasive method. However, the interrupter technique shows a dependence on the shutter speed and breathing direction.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMECHANICAL & PRODUCTION ENGINEERING
dc.description.sourcetitleAnnals of Biomedical Engineering
dc.description.volume19
dc.description.issue5
dc.description.page586-
dc.description.codenABMEC
dc.identifier.isiutNOT_IN_WOS
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