Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jmbbm.2013.11.012
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dc.titleCharacterization of uniaxial stiffness of extracellular matrix embedded with magnetic beads via bio-conjugation and under the influence of an external magnetic field
dc.contributor.authorHerath, S.C.B.
dc.contributor.authorDu, Y.
dc.contributor.authorWang, D.-A.
dc.contributor.authorLiao, K.
dc.contributor.authorWang, Q.
dc.contributor.authorAsada, H.
dc.contributor.authorChen, P.C.Y.
dc.date.accessioned2014-06-17T02:41:16Z
dc.date.available2014-06-17T02:41:16Z
dc.date.issued2014-02
dc.identifier.citationHerath, S.C.B., Du, Y., Wang, D.-A., Liao, K., Wang, Q., Asada, H., Chen, P.C.Y. (2014-02). Characterization of uniaxial stiffness of extracellular matrix embedded with magnetic beads via bio-conjugation and under the influence of an external magnetic field. Journal of the Mechanical Behavior of Biomedical Materials 30 : 253-265. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jmbbm.2013.11.012
dc.identifier.issn17516161
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/55280
dc.description.abstractIn this paper, we study the deformation, and experimentally quantify the change in stiffness, of an extracellular matrix (ECM) embedded with magnetic beads that are bio-conjugated with the collagen fibers and under the influence of an external magnetic field. We develop an analytical model of the viscoelastic behavior of this modified ECM, and design and implement a stretch test to quantify (based on statistically meaningful experiment data) the resulting changes in its stiffness induced by the external magnetic field. The analytical results are in close agreement with that obtained from the experiments. We discuss the implication of these results that point to the possibility of creating desired stiffness gradients in an ECM in vitro to influence cell behavior. © 2013 Elsevier Ltd.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.jmbbm.2013.11.012
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMECHANICAL ENGINEERING
dc.contributor.departmentELECTRICAL & COMPUTER ENGINEERING
dc.description.doi10.1016/j.jmbbm.2013.11.012
dc.description.sourcetitleJournal of the Mechanical Behavior of Biomedical Materials
dc.description.volume30
dc.description.page253-265
dc.identifier.isiut000331493900026
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