Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.icheatmasstransfer.2009.02.013
DC FieldValue
dc.titleA numerical analysis of cell density effect on oxygen transport in a micro-bioreactor with a tissue engineering scaffold
dc.contributor.authorYu, P.
dc.contributor.authorZeng, Y.
dc.contributor.authorLee, T.S.
dc.contributor.authorLow, H.T.
dc.date.accessioned2014-06-16T09:33:26Z
dc.date.available2014-06-16T09:33:26Z
dc.date.issued2009-07
dc.identifier.citationYu, P., Zeng, Y., Lee, T.S., Low, H.T. (2009-07). A numerical analysis of cell density effect on oxygen transport in a micro-bioreactor with a tissue engineering scaffold. International Communications in Heat and Mass Transfer 36 (6) : 569-573. ScholarBank@NUS Repository. https://doi.org/10.1016/j.icheatmasstransfer.2009.02.013
dc.identifier.issn07351933
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/54657
dc.description.abstractThe effect of cell density on the fluid dynamics and oxygen transport in a micro-bioreactor with a tissue engineering scaffold was investigated. Variations of the permeability and porosity of the scaffold with cell density were estimated by a simple model. Based on the permeability and the porosity obtained, the flow and oxygen transport in a micro-bioreactor were simulated numerically. It was found that the flow rate passing through the scaffold is reduced with an increase in cell density. The oxygen concentration within the scaffold also decreases with an increase in cell density, due to lower oxygen convection caused by lower porous flow rate and higher oxygen consumption. The results suggest that, for high cell density culture, the oxygen concentration within the scaffold may be overestimated if the cell density effect is neglected. © 2009 Elsevier Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.icheatmasstransfer.2009.02.013
dc.sourceScopus
dc.subjectCell density
dc.subjectOxygen transfer
dc.subjectTissue-engineering scaffold
dc.typeArticle
dc.contributor.departmentMECHANICAL ENGINEERING
dc.contributor.departmentTEMASEK LABORATORIES
dc.description.doi10.1016/j.icheatmasstransfer.2009.02.013
dc.description.sourcetitleInternational Communications in Heat and Mass Transfer
dc.description.volume36
dc.description.issue6
dc.description.page569-573
dc.description.codenIHMTD
dc.identifier.isiut000267734200007
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

6
checked on Oct 11, 2019

WEB OF SCIENCETM
Citations

4
checked on Jul 2, 2019

Page view(s)

50
checked on Oct 13, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.