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Title: Systemic Associations of Dynamic Retinal Vessel Analysis: A Review of Current Literature
Authors: Lim, M.
Sasongko, M.B.
Ikram, M.K.
Lamoureux, E.
Wang, J.J.
Wong, T.Y. 
Cheung, C.Y. 
Keywords: Cardiovascular diseases
Dynamic vessel analyzer
Endothelial dysfunction
Retinal vascular imaging
Issue Date: Apr-2013
Citation: Lim, M., Sasongko, M.B., Ikram, M.K., Lamoureux, E., Wang, J.J., Wong, T.Y., Cheung, C.Y. (2013-04). Systemic Associations of Dynamic Retinal Vessel Analysis: A Review of Current Literature. Microcirculation 20 (3) : 257-268. ScholarBank@NUS Repository.
Abstract: Endothelial dysfunction is a key pathogenic mechanism of CVD. The retinal microvascular network offers a unique, non-invasive window to study endothelial function. Recently, dynamic measurement of retinal vessel caliber using flicker light stimulation has been used to evaluate potential endothelial dysfunction and other mechanisms in CVD. A variety of studies now indicate that retinal vasodilation during flicker light simulation is reduced in diabetes, hypertension, hyperlipidemia and obesity, and may be influenced by age and race/ethnicity. These data suggest that flicker light-induced retinal vasodilation may be a unique and non-invasive measure of endothelial dysfunction. This review focuses recent studies on systemic associations of flicker light-induced retinal vasodilation, and discusses the potential for future research in this area. © 2012 John Wiley & Sons Ltd.
Source Title: Microcirculation
ISSN: 10739688
DOI: 10.1111/micc.12026
Appears in Collections:Staff Publications

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