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Title: Prevalence of amblyopia and strabismus in young singaporean chinese children
Authors: Chia, A.
Dirani, M.
Chan, Y.-H.
Gazzard, G.
Au Eong, K.-G.
Selvaraj, P.
Ling, Y.
Quah, B.-L.
Young, T.L. 
Mitchell, P.
Varma, R.
Wong, T.-Y. 
Saw, S.-M. 
Issue Date: Jul-2010
Citation: Chia, A., Dirani, M., Chan, Y.-H., Gazzard, G., Au Eong, K.-G., Selvaraj, P., Ling, Y., Quah, B.-L., Young, T.L., Mitchell, P., Varma, R., Wong, T.-Y., Saw, S.-M. (2010-07). Prevalence of amblyopia and strabismus in young singaporean chinese children. Investigative Ophthalmology and Visual Science 51 (7) : 3411-3417. ScholarBank@NUS Repository.
Abstract: Purpose. To determine the prevalence of amblyopia and strabismus in young Singaporean Chinese children. Methods. Enrolled in the study were 3009 Singaporean children, aged 6 to 72 months. All underwent complete eye examinations and cycloplegic refraction. Visual acuity (VA) was measured with a logMAR chart when possible and the Sheridan-Gardner test when not. Strabismus was defined as any manifest tropia. Unilateral amblyopia was defined as a 2-line difference between eyes with VA < 20/30 in the worse eye and with coexisting anisometropia (≥1.00 D for hyperopia, >3.00 D for myopia, and ≥1.50 D for astigmatism), strabismus, or past or present visual axis obstruction. Bilateral amblyopia was defined as VA in both eyes < 20/40 (in children 48-72 months) and <20/50 (<48 months), with coexisting hyperopia >4.00 D, myopia ≤ -6.00 D, and astigmatism ≥2.50 D, or past or present visual axis obstruction. Results. The amblyopia prevalence in children aged 30 to 72 months was 1.19% (95% confidence interval [CI], 0.73-1.83) with no age (P = 0.37) or sex (P = 0.22) differences. Unilateral amblyopia (0.83%) was twice as frequent as bilateral amblyopia (0.36%). The most frequent causes of amblyopia were refractive error (85%) and strabismus (15%); anisometropic astigmatism >1.50 D (42%) and isometropic astigmatism >2.50 D (29%) were frequent refractive errors. The prevalence of strabismus in children aged 6 to 72 months was 0.80% (95% CI, 0.51-1.19), with no sex (P _ 0.52) or age (P _ 0.08) effects. The exotropia-esotropia ratio was 7:1, with most exotropia being intermittent (63%). Of children with amblyopia, 15.0% had strabismus, whereas 12.5% of children with strabismus had amblyopia. CONCLUSIONS. The prevalence of amblyopia was similar, whereas the prevalence of strabismus was lower than in other populations. © Association for Research in Vision and Ophthalmology.
Source Title: Investigative Ophthalmology and Visual Science
ISSN: 01460404
DOI: 10.1167/iovs.09-4461
Appears in Collections:Staff Publications

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