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Title: A questionnaire-based assessment of symptoms associated with tear film dysfunction and lid margin disease in an Asian population
Authors: Tongg, L.
Saw, S.-M. 
Lamoureux, E.L.
Wang, J.J.
Rosman, M.
Tan, D.T.H.
Wong, T.Y. 
Keywords: Cross-sectional study
Dry eye
Ocular surface disease
Issue Date: Feb-2009
Citation: Tongg, L., Saw, S.-M., Lamoureux, E.L., Wang, J.J., Rosman, M., Tan, D.T.H., Wong, T.Y. (2009-02). A questionnaire-based assessment of symptoms associated with tear film dysfunction and lid margin disease in an Asian population. Ophthalmic Epidemiology 16 (1) : 31-37. ScholarBank@NUS Repository.
Abstract: Purpose: To study the prevalence, associated factors and impact of symptomatic dry eye in an Asian population. Methods: A population based survey of eye diseases in 3,280 (78.7% response rate) Malay persons aged 40-80 selected from designated areas in southwestern Singapore. Participants were administered a standardized dry eye questionnaire consisting of 6 questions on symptoms, and had a comprehensive systemic and ocular examination. Symptoms of tear film dysfunction (STFD) was defined as one or more self-reported symptoms that were frequently present (ranked often or all the time). Results: The prevalence rate of STFD was 6.5% (95% confidence interval [CI]: 5.7, 7.4). The prevalence was significantly higher in men compared to women (8.2% and 4.9%, respectively; p < 0.001) and decreased with age in men (p = 0.002) but not in women (p = 0.101). After adjusting for age, gender, nature of work (outdoor/indoor), and housing type, factors significantly associated with STFD were cigarette smoking (odds ratio [OR] 1.77, 95% CI: 1.17-2.66), thyroid disease (OR 2.58; 95% CI: 1.29-5.18) and higher income (OR 1.74; 95% CI: 1.13-2.68). STFD were associated with self-reported difficulty in performing daily activities (work, family and leisure related) (p = 0.006). Conclusion: STFD are present in 6.5% of Singapore Malay adults and is associated with cigarette smoking, presence of thyroid disease and a reduced visual function-related quality of life. Copyright © 2009 Informa Healthcare USA, Inc.
Source Title: Ophthalmic Epidemiology
ISSN: 09286586
DOI: 10.1080/09286580802521317
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