Please use this identifier to cite or link to this item:<207
Title: Screening of traditional medicines for their inhibitory activity against HIV-1 protease
Authors: Xu, H.-X. 
Wan, M.
Loh, B.-N.
Kon, O.-L. 
Chow, P.-W. 
Sim, K.-Y. 
Keywords: Aqueous extracts
Fluorogenic assay
Inhibition of HIV-1 protease
Traditional medicines
Issue Date: May-1996
Citation: Xu, H.-X.,Wan, M.,Loh, B.-N.,Kon, O.-L.,Chow, P.-W.,Sim, K.-Y. (1996-05). Screening of traditional medicines for their inhibitory activity against HIV-1 protease. Phytotherapy Research 10 (3) : 207-210. ScholarBank@NUS Repository.<207
Abstract: Aqueous extracts of 75 different traditional medicines, currently used for the treatment of various human diseases in China, Japan and Indonesia, were screened for possible inhibitory activity against HIV-1 protease using fluorogenic assay. Forty extracts exhibited inhibitory activity at a concentration of 250 μg/mL, and 18 of them inhibited HIV-1 protease activity by more than 70%. Among the extracts examined, Belamcanda chinensis, Magnolia fargesii, Paeonia suffruticosa, Phellodendron amurense and Terminalia chebula were also effective at a concentration of 25 μg/mL in the fluorogenic assay.
Source Title: Phytotherapy Research
ISSN: 0951418X
DOI: 10.1002/(SICI)1099-1573(199605)10:3<207
Appears in Collections:Staff Publications

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