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|Title:||Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore||Authors:||Chen, M.I.C.
|Issue Date:||Oct-2010||Citation:||Chen, M.I.C., Lee, V.J.M., Barr, I., Lin, C., Goh, R., Lee, C., Singh, B., Tan, J., Lim, W.-Y., Cook, A.R., Ang, B., Chow, A., Tan, B.H., Loh, J., Shaw, R., Chia, K.S., Lin, R.T.P., Leo, Y.S. (2010-10). Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore. Emerging Infectious Diseases 16 (10) : 1554-1561. ScholarBank@NUS Repository. https://doi.org/10.3201/eid1610.100516||Abstract:||We describe incidence and risk factors for pandemic (H1N1) 2009 virus infection in healthcare personnel during the June-September 2009 epidemic in Singapore. Personnel contributed 3 serologic samples during June-October2009, with seroconversion defined as a ≥4-fold increase in hemagglutination inhibition titers to pandemic (H1N1) 2009.Of 531 participants, 35 showed evidence of seroconversion. Seroconversion rates were highest in nurses (28/290) and lowest in allied health staff (2/116). Significant risk factor son multivariate analysis were being a nurse (adjusted odd sratio [a OR] 4.5, 95% confidence interval [CI] 1.0-19.6) and working in pandemic (H1N1) 2009 isolation wards (aOR4.5, 95% CI 1.3-15.6). Contact with pandemic (H1N1)2009-infected colleagues (a OR 2.5, 95% CI 0.9-6.6) and larger household size (a OR 1.2, 95% CI 1.0-1.4) were of borderline significance. Our study suggests that seroconversion was associated with occupational and nonoccupational risk factors.||Source Title:||Emerging Infectious Diseases||URI:||http://scholarbank.nus.edu.sg/handle/10635/53138||ISSN:||10806040||DOI:||10.3201/eid1610.100516|
|Appears in Collections:||Staff Publications|
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