Please use this identifier to cite or link to this item: https://doi.org/10.1167/iovs.10-7108
DC FieldValue
dc.titleApplication of advanced statistics in ophthalmology
dc.contributor.authorFan, Q.
dc.contributor.authorTeo, Y.-Y.
dc.contributor.authorSaw, S.-M.
dc.date.accessioned2014-05-19T02:50:07Z
dc.date.available2014-05-19T02:50:07Z
dc.date.issued2011-08
dc.identifier.citationFan, Q., Teo, Y.-Y., Saw, S.-M. (2011-08). Application of advanced statistics in ophthalmology. Investigative Ophthalmology and Visual Science 52 (9) : 6059-6065. ScholarBank@NUS Repository. https://doi.org/10.1167/iovs.10-7108
dc.identifier.issn01460404
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/52791
dc.description.abstractStatistics is an integral part of research in ophthalmology. The application of appropriate statistical strategies allows clinicians to realize the full potential in analyzing data from paired ocular measurements, longitudinal design, and genome-wide association study (GWAS). The increasing popularity of longitudinal follow-up in either clinical or epidemiologic study demands advanced statistical methodologies. This article describes robust statistical models that can cope with correlated components for both paired-eye data and repeated measurements over time. Also highlight are the statistical challenges and corresponding strategies available for testing multiple hypotheses with paired-eye data in GWAS, which has been the subject of intense interest for the past 5 years within the ophthalmology community in investigating the genetic etiology of eye disorders. © 2011 The Association for Research in Vision and Ophthalmology, Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1167/iovs.10-7108
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentSTATISTICS & APPLIED PROBABILITY
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.description.doi10.1167/iovs.10-7108
dc.description.sourcetitleInvestigative Ophthalmology and Visual Science
dc.description.volume52
dc.description.issue9
dc.description.page6059-6065
dc.description.codenIOVSD
dc.identifier.isiut000293849400001
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