Please use this identifier to cite or link to this item: https://doi.org/10.1002/mabi.201100325
DC FieldValue
dc.titleAdvances in Polymeric Systems for Tissue Engineering and Biomedical Applications
dc.contributor.authorRavichandran, R.
dc.contributor.authorSundarrajan, S.
dc.contributor.authorVenugopal, J.R.
dc.contributor.authorMukherjee, S.
dc.contributor.authorRamakrishna, S.
dc.date.accessioned2014-05-16T06:37:32Z
dc.date.available2014-05-16T06:37:32Z
dc.date.issued2012-03
dc.identifier.citationRavichandran, R., Sundarrajan, S., Venugopal, J.R., Mukherjee, S., Ramakrishna, S. (2012-03). Advances in Polymeric Systems for Tissue Engineering and Biomedical Applications. Macromolecular Bioscience 12 (3) : 286-311. ScholarBank@NUS Repository. https://doi.org/10.1002/mabi.201100325
dc.identifier.issn16165187
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/52592
dc.description.abstractThe characteristics of tissue engineered scaffolds are major concerns in the quest to fabricate ideal scaffolds for tissue engineering applications. The polymer scaffolds employed for tissue engineering applications should possess multifunctional properties such as biocompatibility, biodegradability and favorable mechanical properties as it comes in direct contact with the body fluids in vivo. Additionally, the polymer system should also possess biomimetic architecture and should support stem cell adhesion, proliferation and differentiation. As the progress in polymer technology continues, polymeric biomaterials have taken characteristics more closely related to that desired for tissue engineering and clinical needs. Stimuli responsive polymers also termed as smart biomaterials respond to stimuli such as pH, temperature, enzyme, antigen, glucose and electrical stimuli that are inherently present in living systems. This review highlights the exciting advancements in these polymeric systems that relate to biological and tissue engineering applications. Additionally, several aspects of technology namely scaffold fabrication methods and surface modifications to confer biological functionality to the polymers have also been discussed. The ultimate objective is to emphasize on these underutilized adaptive behaviors of the polymers so that novel applications and new generations of smart polymeric materials can be realized for biomedical and tissue engineering applications. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/mabi.201100325
dc.sourceScopus
dc.subjectpH and temperature responsive polymers
dc.subjectSmart polymers
dc.subjectStimuli-responsive polymers
dc.subjectSurface modification
dc.subjectTissue engineering
dc.typeReview
dc.contributor.departmentNUS NANOSCIENCE & NANOTECH INITIATIVE
dc.contributor.departmentMECHANICAL ENGINEERING
dc.description.doi10.1002/mabi.201100325
dc.description.sourcetitleMacromolecular Bioscience
dc.description.volume12
dc.description.issue3
dc.description.page286-311
dc.description.codenMBAIB
dc.identifier.isiut000301052700001
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