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Title: Electrochemical Detection of Dengue Virus using Nanoporous Membrane
Keywords: Impedance, Membrane, Virus, Alumina, Biosensor, Diagnostic
Issue Date: 7-Oct-2013
Citation: PEH EN KAI ALISTER (2013-10-07). Electrochemical Detection of Dengue Virus using Nanoporous Membrane. ScholarBank@NUS Repository.
Abstract: This thesis entails the development and characterisation of membrane-based biosensors for the detection and serotyping of an infecting Dengue virus. The projects aim to explore sensing platforms which can possibly be miniaturised into a point-of-care diagnostic tool. Early disease diagnosis is particularly important since fluid treatment and monitoring is currently the only way to fight against the disease. Anodic aluminium oxide (Alumina) membrane was chosen because of its good mechanical stability and regularity in pore sizes. These nano-sized pores permit high throughput analysis, better sensitivity and selectivity due to their large surface-area-to-volume ratio and close intimation with biomolecules of similar sizes. Electrochemical techniques were employed as the detecting platform because they can be easily miniaturised and the data can be outputted into values easily understood by an end-user.
Appears in Collections:Ph.D Theses (Open)

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