Please use this identifier to cite or link to this item:
|Title:||Remineralization of partially demineralized dentine substrate based on a biomimetic strategy||Authors:||Zhang, X.
|Issue Date:||Mar-2012||Citation:||Zhang, X., Neoh, K.G., Lin, C.C., Kishen, A. (2012-03). Remineralization of partially demineralized dentine substrate based on a biomimetic strategy. Journal of Materials Science: Materials in Medicine 23 (3) : 733-742. ScholarBank@NUS Repository. https://doi.org/10.1007/s10856-012-4550-5||Abstract:||Dentine remineralization is clinically significant for prevention and treatment of dentine caries, root caries, and dentine hypersensitivity. However, dentine remineralization is more difficult than enamel remineralization due to the abundant presence of organic matrix in dentine. The objective of this study was to develop a biomimetic method to facilitate remineralization of demineralized dentine through phosphorylation of type I collagen in demineralized dentine using sodium trimetaphosphate. The experimental results indicated that the effect of fluoride on remineralizing dentine was limited when residual mineral crystals were lacking on the surface of demineralized dentine, whereas the phosphorylation and Ca(OH)2 pretreatment enhanced surface remineralization of the partially demineralized dentine. This biomimetic methodology resulted in favorable surface properties (i.e. highly negative charge and low interfacial free energy between substrate and aqueous medium) for crystal nucleation, and thus could be a promising method to remineralize superficially demineralized dentine lesions. © 2012 Springer Science+Business Media, LLC.||Source Title:||Journal of Materials Science: Materials in Medicine||URI:||http://scholarbank.nus.edu.sg/handle/10635/51813||ISSN:||09574530||DOI:||10.1007/s10856-012-4550-5|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Sep 22, 2020
WEB OF SCIENCETM
checked on Sep 15, 2020
checked on Sep 21, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.