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Title: Application of proteomics in environmental science
Authors: Chu, X. 
Hu, J. 
Ong, S.L. 
Keywords: Environmental stress
Mass spectrometry
Two dimensional (2D) gel electrophoresis
Issue Date: Dec-2009
Citation: Chu, X., Hu, J., Ong, S.L. (2009-12). Application of proteomics in environmental science. Frontiers of Environmental Science and Engineering in China 3 (4) : 393-403. ScholarBank@NUS Repository.
Abstract: Proteomics involves the separation of proteins, identification of the amino acid sequence of the interested or target proteins, study of the function of the proteins, modification, structure and ultimate assignments to functional pathways in the cell. The proteomic investigations have contributed greatly to human diseases studies, new drugs discovery researches, and environmental science in recent years. This article provides a review on the development of the main proteomic technologies, including both the gel based and non-gel based technologies, and their applications in environmental science. Proteomic technologies have been utilized in the environmental stresses studies to analyze the induction or reduction of proteins at expression level and identify the target proteins to investigate their function in response to environmental stresses, such as high or low pH, oxidation stress, and toxic chemicals. Such protein responses are also helpful to understand the mechanisms of some cellular activities and the functions of some proteins. © Higher Education Press and Springer-Verlag 2009.
Source Title: Frontiers of Environmental Science and Engineering in China
ISSN: 16737415
DOI: 10.1007/s11783-009-0145-x
Appears in Collections:Staff Publications

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