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Title: Risk Factors for Gastric Cancer and Risk Stratification in Singapore Chinese Population
Authors: ZHU FENG
Keywords: gastric cancer, risk factors, risk stratification, Singapore Chinese
Issue Date: 12-Apr-2013
Citation: ZHU FENG (2013-04-12). Risk Factors for Gastric Cancer and Risk Stratification in Singapore Chinese Population. ScholarBank@NUS Repository.
Abstract: Gastric cancer (GC) is the second leading cause of cancer death worldwide. Screening is practised in Japan and Korea where the population incidence of GC incidence is high. Early detection by endoscopy screening and surveillance has been shown to reduce mortality rate. It is thought to be not cost-effective to screen the general population in countries with low to intermediate GC incidence rates such as Singapore. Risk stratification to identify individuals at high risk of GC is a potential method to reduce the cost of screening and surveillance. People with precursor lesions such as atrophic gastritis and intestinal metaplasia are believed to be at higher risk of developing GC. This thesis sets out to describe the risk factors for GC in our local population and to explore the possibility of stratifying the Singapore Chinese population into those with low or high risk for GC based on genetic risk factor and precursor lesions of GC.
Appears in Collections:Ph.D Theses (Open)

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