Fluorescence Based Sensor for Low Cost Blister Detection

Abstract

In this thesis, we explored and demonstrated the feasibility of fluorescence detection techniques for half sulfur mustard (HSM) sensing. HSM was investigated due to its structural similarity with sulfur mustard (HD); less one chlorine group. HD belongs to a class of blister agents that has the ability to cause blistering on contact, incapacitating troops of people during a chemical attack. Currently, detectors with the capability to detect and identify HD are mostly bulky and costly. There is a need to look into miniaturised, low cost sensors that are lightweight and desirably, easy-to-use. Owing to recent developments in the availability of inexpensive optical components and the existing chemistries for detection of chemical agents, fluorescence based optical chemical sensors may be the ideal candidate. Different fluorometric based platforms were thus developed and they revealed the potential in HSM sensing. Detection capabilities such as sensitivity, selectivity and reliability were also evaluated.