Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/49360
DC FieldValue
dc.titleMOLECULAR AND NANOSCALE LUMINESCENT PROBES FOR DETECTION OF REACTIVE OXYGEN SPECIES
dc.contributor.authorYAN YAN
dc.date.accessioned2014-02-28T18:00:40Z
dc.date.available2014-02-28T18:00:40Z
dc.date.issued2013-07-23
dc.identifier.citationYAN YAN (2013-07-23). MOLECULAR AND NANOSCALE LUMINESCENT PROBES FOR DETECTION OF REACTIVE OXYGEN SPECIES. ScholarBank@NUS Repository.
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/49360
dc.description.abstractReactive oxygen species (ROS) are generated as byproducts or intermediates of the normal metabolism of oxygen. ROS play significant roles in cell signaling, homeostasis, and host defense. However, the excessive production of ROS may result in significant damage to cell structures and lead to a situation known as oxidative stress. To figure out multiple roles and action mechanisms of ROS, it is essential to develop sensitive and selective methods for ROS sensing in biological system. Among various approaches, fluorescent probes are preferred because they allow spatial and temporal monitoring and visually tracking ROS in cells and tissues. Here we present successfully developed molecular and nanoscale fluorescent probes targeting on ROS. These probes have been utilized in biological sensing, such as myeloperoxidase activity monitoring, live cell imaging and quantifying ROS scavenging ability of tea catechins, and also in environmental monitoring, like visual detection of trace amount of air pollutant in atmosphere.
dc.language.isoen
dc.subjectfluorescent probe, reactive oxygen species, transition metal complexes, quantum dots, nitrogen dioxide, hypochlorite
dc.typeThesis
dc.contributor.departmentCHEMISTRY
dc.contributor.supervisorHUANG DEJIAN
dc.contributor.supervisorHAN MING YONG
dc.description.degreePh.D
dc.description.degreeconferredDOCTOR OF PHILOSOPHY
dc.identifier.isiutNOT_IN_WOS
Appears in Collections:Ph.D Theses (Open)

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
YanYan_PhD thesis_Final_131222.pdf8.25 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

124
checked on May 22, 2019

Download(s)

57
checked on May 22, 2019

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.