Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0264-410X(02)00245-1
Title: A comparison of safety, tolerability and immunogenicity of Oka/Merck varicella vaccine and VARILRIX™ in healthy children
Authors: Lau, Y.-L.
Lee, T.-L.
Vessey, S.J.R.
Chan, I.S.F.
Chan, C.Y.
Kaplan, K.M.
Distefano, D.J.
Harmon, A.L.
Golie, A.
Hartzel, J.
Xu, J.
Li, S.
Matthews, H.
Sadoff, J.C.
Shaw, A.
Huang, L.-M.
Lee, C.-Y.
Lin, T.-Y.
Lee, B.W. 
Kwan, K.
Kasim, S.M.
Keywords: Immunogenicity
Varicella vaccination
Varicella zoster virus
Issue Date: 2002
Citation: Lau, Y.-L., Lee, T.-L., Vessey, S.J.R., Chan, I.S.F., Chan, C.Y., Kaplan, K.M., Distefano, D.J., Harmon, A.L., Golie, A., Hartzel, J., Xu, J., Li, S., Matthews, H., Sadoff, J.C., Shaw, A., Huang, L.-M., Lee, C.-Y., Lin, T.-Y., Lee, B.W., Kwan, K., Kasim, S.M. (2002). A comparison of safety, tolerability and immunogenicity of Oka/Merck varicella vaccine and VARILRIX™ in healthy children. Vaccine 20 (23-24) : 2942-2949. ScholarBank@NUS Repository. https://doi.org/10.1016/S0264-410X(02)00245-1
Abstract: This study compared safety, tolerability, and immunogenicity of the Oka/Merck varicella vaccine and VARILRIX™ [Oka-RIT strain SmithKline Beecham Biologicals] in healthy children 12-24 months of age. Subjects were randomized in this double blind study to receive either a single dose of Oka/Merck varicella vaccine, (∼50,000 plaque forming units (PFU), Group A or ∼16,000PFU, Group B) or 1 dose of VARILRIX™, (∼40,000PFU/dose, Group C). Safety profiles in each treatment group were similar. The proportions of subjects achieving a 6-week postvaccination titer ≥5 gpELISA units in Groups A, B or C were 97.1, 95.2 and 85.6%, respectively. © 2002 Elsevier Science Ltd. All rights reserved.
Source Title: Vaccine
URI: http://scholarbank.nus.edu.sg/handle/10635/48033
ISSN: 0264410X
DOI: 10.1016/S0264-410X(02)00245-1
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