Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/46680
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dc.titleAirway and craniofacial changes with mandibular advancement device in Chinese with obstructive sleep apnoea
dc.contributor.authorPoon, K.H.
dc.contributor.authorChay, S.H.
dc.contributor.authorChiong, K.F.W.
dc.date.accessioned2013-10-16T05:35:59Z
dc.date.available2013-10-16T05:35:59Z
dc.date.issued2008
dc.identifier.citationPoon, K.H.,Chay, S.H.,Chiong, K.F.W. (2008). Airway and craniofacial changes with mandibular advancement device in Chinese with obstructive sleep apnoea. Annals of the Academy of Medicine Singapore 37 (8) : 637-644. ScholarBank@NUS Repository.
dc.identifier.issn03044602
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/46680
dc.description.abstractIntroduction: The objective of this study was to investigate whether a reduction of obstructive sleep apnoea (OSA) severity is associated with significant air way and craniofacial changes with mandibular advancement device (MAD) in Chinese subjects. Materials and Methods: A total of 14 Chinese subjects (8 males, 6 females) diagnosed with OSA by overnight polysomnography (PSG), were fitted with the MAD. The mean ± standard deviation baseline apnoea-hypopnoea index (AHI) was 38.4±17.2 and minimum arterial oxygen saturation (SaO2) was 75.5 ± 11.1% . The second lateral cephalogram was taken (wearing the MAD) after the second PSG. The second PSG was indicated when symptoms have improved as shown by the Epworth Sleepiness Score and sleep questionnaire after wearing the MAD for 1 month. Comparison of cephalometric variables was done to evaluate the effects of the MAD on the upper airway and anatomical variables. Pre-treatment versus post-treatment variables were compared using Wilcoxon signed-rank test to determine the statistical significance at the 5% levels. The changes in airway variables were correlated with the changes in AHI using the Spearman correlation test. Results: At the second polysomnogram, AHI was significantly reduced to 10.9 ± 14.7. Minimum SaO2 was significantly increased to 86 ± 8.4% . Mean airway dimension was significantly increased at the nasopharyngeal area from 22.7 ± 3.0 mm to 24.8 ± 2.1 mm. The distance of the hyoid bone to the mandibular plane was significantly reduced with the MAD from a mean of 21.2 ±5.7 mm to 13.9 ± 7.0 mm (P <0.05). This reduction of the distance of the hyoid bone to the mandibular plane was significantly correlated with the reduction in the AHI. Conclusion: An increase in the nasopharyngeal airway and reduction of the distance of the hyoid bone to the mandibular plane was observed for this sample of Chinese OSA subjects. This study forms thebaseline for future studies on the effects of MAD on the airway and craniofacial structures in a larger sample.
dc.sourceScopus
dc.subjectLateral cephalogram
dc.subjectMandibular advancement device
dc.subjectMandibular advancement splint
dc.subjectObstructive sleep apnoea
dc.subjectPolysomnogram
dc.typeArticle
dc.contributor.departmentPREVENTIVE DENTISTRY
dc.description.sourcetitleAnnals of the Academy of Medicine Singapore
dc.description.volume37
dc.description.issue8
dc.description.page637-644
dc.description.codenAAMSC
dc.identifier.isiutNOT_IN_WOS
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