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|Title:||Use of artemisinin derivatives for the treatment of asthma and chronic obstructive pulmonary disease (COPD)||Authors:||WONG, WAI SHIU FRED||Issue Date:||23-Oct-2012||Citation:||WONG, WAI SHIU FRED (2012-10-23). Use of artemisinin derivatives for the treatment of asthma and chronic obstructive pulmonary disease (COPD). ScholarBank@NUS Repository.||Abstract:||Artesunate is a derivative of artemisinin isolated from a Chinese herb Artemisia annua L. It is used clinically for the treatment of malaria. We investigated potential anti-inflammatory actions of artemisinin derivatives. artemisinin derivatives significantly inhibited OVA-induced signs, symptoms and parameter of airway disorders Taken together, our results clearly demonstrate anti-inflammatory effects of artemisinin derivatives. Artemisinin derivatives can be used to complement or to replace oral steroids during asthma exacerbation treatment. Further artemisinin derivatives can be used as an anti-inflammatory agent for controlling airway disorders. ##STR00001##||URI:||http://scholarbank.nus.edu.sg/handle/10635/43453|
|Appears in Collections:||Staff Publications|
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