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|Title:||Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro||Authors:||Too, H.-P.
Polymerase chain reaction
Substance P receptor
|Issue Date:||1994||Citation:||Too, H.-P., Marriott, D.R., Wilkin, G.P. (1994). Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro. Neuroscience Letters 182 (2) : 185-187. ScholarBank@NUS Repository. https://doi.org/10.1016/0304-3940(94)90793-5||Abstract:||The presence of mRNA transcripts coding for preprotachykinin-A and the substance P receptor in cultured astrocytes is demonstrated by a combination of reverse transcription/polymerase chain reaction (PCR) and Southern blotting. These findings showed that astroyctes in culture are capable of synthesing both the precursor of substance P (preprotachykinin-A) and the cognate receptor, substance P receptor (NK1). The simultaneous presence of both the ligand (substance P) and the receptor (NK1)) may indicate an autocrine nature of astrocyte communication.||Source Title:||Neuroscience Letters||URI:||http://scholarbank.nus.edu.sg/handle/10635/38252||ISSN:||03043940||DOI:||10.1016/0304-3940(94)90793-5|
|Appears in Collections:||Staff Publications|
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