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https://scholarbank.nus.edu.sg/handle/10635/37624
| Title: | ENCAPSULATION OF PLATINUM-BASED DERIVATIVES WITHIN CARBON NANOTUBES: INVESTIGATIONS ON CONTROLLED RELEASE AND IN VIVO BIODISTRIBUTION | Authors: | LI JIAN | Keywords: | carbon nanotube, platinum-based derivatives, drug delivery, controlled release, encapsulation, biodistribution | Issue Date: | 11-Jan-2013 | Citation: | LI JIAN (2013-01-11). ENCAPSULATION OF PLATINUM-BASED DERIVATIVES WITHIN CARBON NANOTUBES: INVESTIGATIONS ON CONTROLLED RELEASE AND IN VIVO BIODISTRIBUTION. ScholarBank@NUS Repository. | Abstract: | This dissertation provides a proof-of-concept on MWCNTs capable of entrapping platinum-based derivatives with high drug loading, and selectively releasing them under pathological conditions. Furthermore, MWCNT-assisted delivery could have an impact on tissue distribution, thus probably exerting an improved pharmacological action and attenuating side effects on non-targeted organs in comparison with drugs alone. | URI: | http://scholarbank.nus.edu.sg/handle/10635/37624 |
| Appears in Collections: | Ph.D Theses (Open) |
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| Fig. 6.2.JPG | 274.92 kB | JPEG | OPEN | None |  View/Download | |
| Fig. 6.3.jpg | 1.8 MB | JPEG | OPEN | None |  View/Download | |
| LiJ.pdf | 6.53 MB | Adobe PDF | OPEN | None | View/Download |
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