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Title: Planning and scheduling in pharmaceutical supply chains
Keywords: Planning, Scheduling, Pharmaceutical plants, Decision-support tools, Optimization, MILP
Issue Date: 21-Aug-2012
Citation: SUSARLA NARESH (2012-08-21). Planning and scheduling in pharmaceutical supply chains. ScholarBank@NUS Repository.
Abstract: The global pharmaceutical industry is grappling with tremendous turmoil in the marketplace and dramatically changing competitive landscape. Fierce market competition, peaking patent cliffs, mounting R&D costs, shrinking product pipelines and stringent regulatory protocols have brought a complete paradigm shift in the way pharmaceutical enterprises operate. Here, we identify a number of critical challenges in supply chain operations and managerial decision making and propose methods to address them. The focus is mainly on developing appropriate decision-support models and tools to address challenges that assist long-term planning decisions. We present a few mathematical models and tools that assist production and operational planning for either a single pharmaceutical plant or an entire global enterprise. The comprehensiveness of our approach and models in considering a close to real problem with scenarios such as multiple products, changeovers, maintenance, new product introductions, transfer prices, duties, taxes, safety stocks, and shelf?lives makes them industrially useful.
Appears in Collections:Ph.D Theses (Open)

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