Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/37171
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dc.titleResponses of polycystic ovarian syndrome and related variants to low-dose follicle stimulating hormone
dc.contributor.authorYong, E.L.
dc.contributor.authorNg, S.C.
dc.contributor.authorChan, C.
dc.contributor.authorKumar, J.
dc.contributor.authorTeo, L.S.
dc.contributor.authorRatnam, S.
dc.date.accessioned2013-04-10T03:03:05Z
dc.date.available2013-04-10T03:03:05Z
dc.date.issued1997
dc.identifier.citationYong, E.L., Ng, S.C., Chan, C., Kumar, J., Teo, L.S., Ratnam, S. (1997). Responses of polycystic ovarian syndrome and related variants to low-dose follicle stimulating hormone. International Journal of Gynecology and Obstetrics 57 (3) : 305-311. ScholarBank@NUS Repository.
dc.identifier.issn00207292
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/37171
dc.description.abstractObjective: To determine whether patients with classical polycystic ovarian syndrome (PCOS) respond differently to low-dose FSH therapy in comparison with anovulatory patients (PCOS-like) where only some features of PCOS are present. Methods: Two groups of patients were studied. The PCOS group (25 patients, 51 cycles) and the PCOS-like group (38 patients, 57 cycles) were treated with the same protocol of purified FSH, commencing with an initial dosage of 75 IU/day and increasing by 37.5 IU/day after 14 days, where necessary. Estradiol levels and ultrasonographic evidence of follicular development were used for monitoring. Results: PCOS patients required more ampules of FSH, needed more days of gonadotropin stimulation, secreted higher levels of E2 and had increased numbers of intermediate follicles compared to the PCOS-like group. Conclusions: This study demonstrated significant differences between PCOS and other PCOS-like conditions when treated with low-dose FSH. Classification of the subvariants of PCOS may have therapeutic implications.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/S0020-7292(97)00072-6
dc.sourceScopus
dc.subjectChronic low-dose FSH
dc.subjectPolycystic ovarian syndrome
dc.subjectPolycystic ovarian syndrome-like
dc.typeArticle
dc.contributor.departmentOBSTETRICS & GYNAECOLOGY
dc.description.sourcetitleInternational Journal of Gynecology and Obstetrics
dc.description.volume57
dc.description.issue3
dc.description.page305-311
dc.description.codenIJGOA
dc.identifier.isiutA1997XG30400009
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