Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/35478
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dc.titleCHOLESTEROL BIOSYNTHESIS PATHWAY MODULATORS AND USES THEREOF
dc.contributorNATIONAL UNIVERSITY OF SINGAPORE
dc.contributor.authorJEYASEELAN, KANDIAH
dc.contributor.authorARMUGAM, ARUNMOZHIARASI
dc.contributor.authorCHAI, SIAW CHING
dc.contributor.authorRAMKISHEN, PRABHAKARAN N
dc.contributor.authorGOPALAKRISHNAKONE, PONNAMPALAM
dc.contributor.authorTAN, KWONG HUAT BENNY
dc.date.accessioned2012-11-21T08:58:26Z
dc.date.available2012-11-21T08:58:26Z
dc.date.issued2004-12-16
dc.identifier.citationJEYASEELAN, KANDIAH,ARMUGAM, ARUNMOZHIARASI,CHAI, SIAW CHING,RAMKISHEN, PRABHAKARAN N,GOPALAKRISHNAKONE, PONNAMPALAM,TAN, KWONG HUAT BENNY (2004-12-16). CHOLESTEROL BIOSYNTHESIS PATHWAY MODULATORS AND USES THEREOF. ScholarBank@NUS Repository.
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/35478
dc.description.abstractAn isolated peptide comprising the amino acid sequence of SEQ ID NO: 2, or a variant, derivative and/or fragment thereof having the function of HMGCoA reductase inhibitor, phosphomevalonate inhibitor, reducing the accumulation of cholesterol in the cholesterol biosynthesis pathway and/or reducing the level of serum cholesterol. Also disclosed is a pharmaceutical composition comprising the peptide having sequence SEQ ID NO:2 or a variant, derivative and/or fragment thereof. Also disclosed is a method for treatment or prophylaxis of disorders characterised by the accumulation of cholesterol, its by-products and/or related lipid derived products, comprising administering to a subject in need at least one peptide comprising the amino acid sequence of SEQ ID NO: 2, or a variant, derivative and/or fragment thereof.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/http://analytics.patsnap.com/patent_view/view?pn=WO2004108928A1
dc.sourcePatSnap
dc.typePatent
dc.contributor.departmentBIOCHEMISTRY
dc.contributor.departmentANATOMY
dc.contributor.departmentPHARMACOLOGY
dc.identifier.isiutNOT_IN_WOS
dc.description.patentnoWO2004108928A1
dc.description.patenttypePublished Application
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