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https://scholarbank.nus.edu.sg/handle/10635/35306
Title: | THE USE OF DES-ASPARTATE-ANGIOTENSIN I AS AN ANTI-CARDIAC HYPERTROPHIC AGENT | Authors: | SIM, MENG KWOON | Issue Date: | 28-Nov-1996 | Citation: | SIM, MENG KWOON (1996-11-28). THE USE OF DES-ASPARTATE-ANGIOTENSIN I AS AN ANTI-CARDIAC HYPERTROPHIC AGENT. ScholarBank@NUS Repository. | Abstract: | The use of des-Aspartate-angiotensin I (Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu) as an anti-cardiac hypertrophic agent is described. The compound, given either intravenously or orally, prevented the development of experimentally-induced cardiac hypertrophy in rats. Its action was dose-dependent and the maximum anti-cardiac hypertrophic effect was obtained at a dose of (i) 180 mg/day when given intravenously, and (ii) 285 mg/day when given orally. | URI: | http://scholarbank.nus.edu.sg/handle/10635/35306 |
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